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doi: 10.1089/jmf.2017.0120

AHK-Cu is structurally related to other copper peptide systems, but differs by its alanine-histidine-lysine sequence, which may contribute to distinct receptor interactions and experimental behavior compared with glycine-based copper tripeptides

It triggers production of antioxidant response elements and intermediates that work to regulate energy homeostatis.1 In vitro data suggests MOTs-C interacts with a variety of pathways, including activating the JAK pathway (impact on aging), inhibiting mTOR signaling (immune and aging impact), inhibition of STAT3 (improved muscle function), activation of ERK pathway (obesity prevention), and translocation of GLUT4 (reduced insulin resistance).2,3 In response to this in vitro data, animal studies to determine actual biological impact have evaluated the impact of exogenous MOTs-C on the body

While it can exhibit cytotoxic effects, it also contributes to immune responses and is essential for the functioning and development of neurons

Some research suppliers sell 5-Amino-1MQ as a lyophilized (freeze-dried) 50 mg vial

Still, animal products may also contain other substances that can interfere with vitamin B12 absorption, so vegetarians and vegans may be at risk of deficiency